In case you do accidentally spill the toner powder:
On your skin:
If the spill has just happened then cold water will get the toner off your skin. Don't use hot or warm water as it softens the toner which then sticks.
If the toner is hard to remove from skin with cold water then it will eventually wear off or can be partially removed with some hand cleaners.
On your clothes:
If you can, as soon as it happens remove clothing and shake out any loose toner. Do this outside so you it doesn't get anywhere else. Don't brush or rub it.
Put 1 tbsp of liquid washing detergent directly on the stain and blot it with a cloth. Then dampen another cloth with cold water and dab at the stain. Finally wash on a cold water setting. If there is still a stain repeat the whole process again then dry.
Toner powder consists of small particles so should not be vacuumed with a conventional home vacuum cleaner as it can damage the vacuum cleaner. Toner particles are so fine that an ordinary vacuum can't filter it properly and can blow straight through the vacuum motor or into the room.
If toner spills into the machine, again it is not advised to use a conventional vacuum. You may have to remove all parts and cartridges affected to clean or use an printer engineer if the spill is bad.